  
{"id":18738,"date":"2026-03-30T08:47:49","date_gmt":"2026-03-30T08:47:49","guid":{"rendered":"https:\/\/www.diginerve.com\/blogs\/?p=18738"},"modified":"2026-03-30T08:53:17","modified_gmt":"2026-03-30T08:53:17","slug":"physiology-important-questions-neet-pg-2026","status":"publish","type":"post","link":"https:\/\/www.diginerve.com\/blogs\/physiology-important-questions-neet-pg-2026\/","title":{"rendered":"Physiology Important Questions for NEET PG 2026"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Preparing for NEET PG requires a strong foundation in basic sciences, and <\/span><b>Physiology<\/b><span style=\"font-weight: 400;\"> is one of the most important subjects. Not only does it form the base for clinical subjects, but it also contributes a significant number of questions in the exam. If you are targeting a high rank, focusing on the important Physiology questions for <a href=\"https:\/\/www.diginerve.com\/blogs\/neet-pg-important-dates-eligibility-criteria-application-process-admit-card\/\"><strong>NEET PG 2026<\/strong><\/a> can give you a strategic advantage.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this blog, we will cover high-yield topics, covered questions, Previous year question and frequently asked questions, to master Physiology effectively.<\/span><\/p>\n<p><b>Q1. A 60-year-old male presents with dyspnea and pedal oedema. Echocardiography shows decreased ejection fraction. Which of the following is the most sensitive indicator of left ventricular function?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Stroke volume<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Cardiac output<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Ejection fraction<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. End-diastolic volume<\/span><\/p>\n<p><b>Answer: C. Ejection fraction<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Ejection fraction (EF) reflects the percentage of blood ejected from the left ventricle during systole. It is the <\/span><b>best indicator of LV systolic function<\/b><span style=\"font-weight: 400;\">, commonly reduced in heart failure.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q2. A patient has increased preload. According to Frank-Starling&#8217;s law, what will happen?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Decrease in stroke volume<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Increase in stroke volume<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. No change<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Decrease in contractility<\/span><\/p>\n<p><b>Answer: B. Increase in stroke volume<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Frank-Starling mechanism states that <\/span><b>increased ventricular filling (preload)<\/b><span style=\"font-weight: 400;\"> leads to increased myocardial stretch \u2192 stronger contraction \u2192 increased stroke volume.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q3. A patient with hypertension is given a drug that decreases peripheral resistance. Which parameter will increase immediately?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Afterload<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Stroke volume<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Heart rate<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Venous return<\/span><\/p>\n<p><b>Answer: B. Stroke volume<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Decreased peripheral resistance \u2192 decreased afterload \u2192 easier ejection \u2192 increased stroke volume.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q4. A patient at high altitude develops breathlessness. Which of the following shifts the oxygen dissociation curve to the right?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Decreased 2,3-BPG<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Decreased CO\u2082<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Increased temperature<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Increased pH<\/span><\/p>\n<p><b>Answer: C. Increased temperature<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Right shift occurs with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u2191 CO\u2082<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u2191 Temperature<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u2191 2,3-BPG<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u2193 pH<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">This facilitates oxygen unloading to tissues.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q5. A premature baby develops respiratory distress syndrome. The primary defect is:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Increased surface tension<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Decreased lung compliance<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Surfactant deficiency<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Increased dead space<\/span><\/p>\n<p><b>Answer: C. Surfactant deficiency<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Surfactant reduces alveolar surface tension. Its deficiency leads to <\/span><b>alveolar collapse (atelectasis)<\/b><span style=\"font-weight: 400;\"> and respiratory distress.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q6. A patient with pulmonary embolism has increased dead space. What does this indicate?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Decreased ventilation<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Increased perfusion<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Ventilation without perfusion<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Perfusion without ventilation<\/span><\/p>\n<p><b>Answer: C. Ventilation without perfusion<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Dead space = ventilated but not perfused areas \u2192 classic in pulmonary embolism.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q7. A patient with severe dehydration has reduced GFR. Which mechanism helps maintain GFR?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Afferent arteriole constriction<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Efferent arteriole constriction<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Increased Bowman pressure<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Decreased plasma proteins<\/span><\/p>\n<p><b>Answer: B. Efferent arteriole constriction<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Angiotensin II causes <\/span><b>efferent arteriole constriction<\/b><span style=\"font-weight: 400;\">, maintaining glomerular pressure and GFR.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q8. A diabetic patient presents with glycosuria. This occurs when:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Plasma glucose &lt;100 mg\/dL<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Plasma glucose &gt;180 mg\/dL<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Insulin increases<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. GFR decreases<\/span><\/p>\n<p><b>Answer: B. Plasma glucose &gt;180 mg\/dL<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Renal threshold for glucose \u2248 is <\/span><b>180 mg\/dL<\/b><span style=\"font-weight: 400;\">. Above this, glucose appears in urine.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q9. A patient develops metabolic acidosis. Which renal mechanism compensates?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Decreased H<\/span><span style=\"font-weight: 400;\">\u207a<\/span><span style=\"font-weight: 400;\"> secretion<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Increased bicarbonate excretion<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Increased H<\/span><span style=\"font-weight: 400;\">\u207a<\/span><span style=\"font-weight: 400;\"> secretion<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Decreased ammonia production<\/span><\/p>\n<p><b>Answer: C. Increased H<\/b><b>\u207a<\/b><b> secretion<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Kidneys compensate by:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u2191 H<\/span><span style=\"font-weight: 400;\">\u207a<\/span><span style=\"font-weight: 400;\"> excretion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">\u2191 bicarbonate reabsorption<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><b>Q10. A patient presents with muscle weakness. A defect in acetylcholine receptors is suspected. Site of action?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. CNS synapse<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Neuromuscular junction<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Autonomic ganglion<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Cerebellum<\/span><\/p>\n<p><b>Answer: B. Neuromuscular junction<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Acetylcholine acts at the <\/span><b>NMJ<\/b><span style=\"font-weight: 400;\"> to cause muscle contraction. Seen in conditions like <\/span><b>Myasthenia Gravis<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q11. A lesion in the cerebellum leads to:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Paralysis<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Loss of coordination<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Loss of sensation<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Aphasia<\/span><\/p>\n<p><b>Answer: B. Loss of coordination<\/b><\/p>\n<p><span style=\"font-weight: 400;\">The cerebellum controls <\/span><b>coordination and balance<\/b><span style=\"font-weight: 400;\">, not strength.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q12. In multiple sclerosis, conduction velocity decreases due to:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Axonal damage only<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Demyelination<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Increased synaptic transmission<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Increased sodium channels<\/span><\/p>\n<p><b>Answer: B. Demyelination<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Myelin enables <\/span><b>saltatory conduction<\/b><span style=\"font-weight: 400;\">. Loss \u2192 slowed conduction.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q13. A patient with hyperparathyroidism will show:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Hypocalcemia<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Hypercalcemia<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Hyperphosphatemia<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Decreased bone resorption<\/span><\/p>\n<p><b>Answer: B. Hypercalcemia<\/b><\/p>\n<p><span style=\"font-weight: 400;\">PTH increases:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bone resorption<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Calcium reabsorption<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">\u2192 \u2191 serum calcium<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><b>Q14. A diabetic patient is given insulin. Which effect is expected?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Increased gluconeogenesis<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Increased glycogen synthesis<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Increased lipolysis<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Decreased glucose uptake<\/span><\/p>\n<p><b>Answer: B. Increased glycogen synthesis<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Insulin promotes:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glucose uptake<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glycogen formation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fat storage<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><b>Q15. A patient with Zollinger-Ellison syndrome shows increased:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Gastrin<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Secretin<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Somatostatin<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Insulin<\/span><\/p>\n<p><b>Answer: A. Gastrin<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Gastrinoma \u2192 \u2191 gastrin \u2192 excessive acid secretion.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q16. A patient has fat malabsorption. Which substance is deficient?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Pepsin<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Trypsin<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Bile salts<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Amylase<\/span><\/p>\n<p><b>Answer: C. Bile salts<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Bile salts are essential for <\/span><b>fat emulsification and absorption<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q17. Bohr effect refers to:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. CO\u2082 transport<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Shift of O\u2082 dissociation curve<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. RBC production<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Haemoglobin breakdown<\/span><\/p>\n<p><b>Answer: B<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Bohr effect = effect of CO\u2082\/pH on Hb-O\u2082 affinity.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q18. Most effective buffer in the blood is:<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Phosphate<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Protein<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Bicarbonate<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. Hemoglobin<\/span><\/p>\n<p><b>Answer: C<\/b><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">The bicarbonate buffer system is the <\/span><b>most important extracellular buffer<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q19. A patient with hyperkalemia shows which ECG change?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Flattened T wave<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Peaked T wave<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. Prolonged QT<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. ST depression<\/span><\/p>\n<p><b>Answer: B<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Hyperkalemia \u2192 <\/span><b>peaked T waves<\/b><span style=\"font-weight: 400;\">, risk of arrhythmia.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><b>Q20. Which condition increases 2,3-BPG?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">A. Anemia<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">B. Hypoxia<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">C. High altitude<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">D. All of the above<\/span><\/p>\n<p><b>Answer: D<\/b><\/p>\n<p><span style=\"font-weight: 400;\">All these conditions shift the curve to the right \u2192 improve oxygen delivery.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">These important Physiology MCQs for NEET PG 2026 reflect:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Clinical integration<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Concept-based learning<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">PYQ patterns<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">To score high:<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Focus on mechanisms, not facts<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Practice clinical MCQs daily<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Revise high-yield topics multiple times<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Preparing for NEET PG requires a strong foundation in basic [&hellip;]<\/p>\n","protected":false},"author":16,"featured_media":17771,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[411],"tags":[821,936,934,935],"class_list":["post-18738","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-physiology","tag-neet-pg-2026","tag-neet-pg-physiology","tag-physiology-important-questions","tag-physiology-mcqs"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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